The purpose of this study was to assess acceptability of Immunization Services against infant killer diseases among women of childbearing age in Kano State Nigeria. To achieve this purpose, multi-stage sampling technique involving simple, stratified, purposive, proportionate and systematic random sampling techniques was used to select 420 women of childbearing age from twelve (12) primary healthcare centres in Kano state. A researcher-developed questionnaire was used in collecting data from the selected hospitals in the three (3) senatorial zones of Kano state. Descriptive statistics of frequencies and percentage, mean and standard deviation and inferential statistics of one-sample t-test was used to analyse the gathered data at alpha level of 0.05. The findings of the study revealed that there was no significant acceptability of immunization services against infant killer diseases among women of childbearing age in Kano state. In conclusion, the findings of the study revealed that women of childbearing age in Kano state do not accept immunization services against infant killer diseases. It was therefore recommended that the government and nongovernmental organizations should mount periodic public awareness campaign on immunization in order to increase the level of acceptance of immunization services by women of childbearing age.